Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment. CIPN symptoms vary from patient to patient, but in general, side effects include: feeling of numbness or "pins and needles" in your hands and feet; difficulty picking up an object or buttoning clothing; ringing in your ears or loss of hearing; changes in vision; sudden, stabbing pains in your hands or feet; constipation/difficulty urinating; muscle weakness or cramps; loss of balance or having ...